Research Compounds
NAD
Options: 100 / 500 / 1000 mg per vialBox of 10 vials
3 variantsFrom$59.00per box
View optionsQuinolinium small molecule
5-Amino-1MQ
5-Amino-1MQ is a small-molecule NNMT inhibitor studied in cellular and mouse metabolic models. It is not a peptide; the commercial salt requires confirmation.
Subtotal excludes freight and taxes. Availability and final terms are confirmed in the quote. Commercial and shipping terms
Mechanism and findings
Mechanism of action
5-Amino-1MQ — quinolinium small molecule. The literature identity must be matched to the documented chemical form and composition of the supplied material.
NNMT uses nicotinamide and SAM to form 1-methylnicotinamide. The methylquinolinium inhibitor study examined permeability and selectivity, along with lipogenesis and metabolites in adipocytes. Inhibitor experiments in mice are distinct from NNMT gene-silencing experiments; the oxygen-consumption increase cited in the supplied profile is not attributed here to 5-Amino-1MQ.
- NNMT
Sources and studies 1
- Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice.
Neelakantan H, Vance V, Wetzel MD, Wang HL, McHardy SF, Finnerty CC, Hommel JD, Watowich SJ · 2018 · Biochemical pharmacology
DOI: 10.1016/j.bcp.2017.11.007
Specifications and packaging
Nominal variant content; analytical results belong to the documented batch.
- Material type
- Small molecule
Quality and analyses
Review specifications, analytical results and documentation for published batches.
- Purity
- >99%
- Type
- Declared specification
Published batches
Batch results have not yet been published on this page.
Storage
Consult the specific conditions in the supplied material documentation.
Delivery and commercial terms
Freight, timing and import terms will be confirmed in the quote for the selected destination.
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