BLOPEPBOLANG BIOTECHNOLOGY

Kisspeptin fragment

Kisspeptin-10

Kisspeptin-10 is investigated in reproductive neuroendocrine signaling. Experimental work examines kisspeptin-responsive GnRH neurons in mice.

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Mechanism and findings →

Mechanism and findings

Animal study · Study formulation · Mouse GnRH neurons across developmental stages

GnRH neuron excitability

Neuronal responsiveness to kisspeptin differed with developmental stage in mice.

Han et al., 2005 →

Literature findings; refer to the model and formulation studied.

Mechanism of action

Kisspeptin-10 — kisspeptin fragment. The literature identity must be matched to the documented chemical form and composition of the supplied material.

Kisspeptin–GPR54 signaling was studied through GnRH neuron depolarization in mice. The proportion of responsive neurons varied with development, alongside changes in KiSS-1 expression. This describes experimental neuroendocrine regulation, not a human reproductive outcome.

  • KISS1R / GPR54

Han et al., 2005

Studied findings 1
Animal study · Study formulation

GnRH neuron excitability

Mouse GnRH neurons across developmental stages

Neuronal responsiveness to kisspeptin differed with developmental stage in mice.

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Study design
Original-study abstract; experimental design described in linked source
Sample scope / arm
Not extracted; consult original study
Comparator
See original-study context
Experimental context (not instructions for use)
Abstract-level extraction; full methods and tables still require review.
Source section / table / abstract
Abstract

Evidence concerns the studied material and model, not the supplied BLOPEP batch.

Han et al., 2005

Sources and studies 2
  1. Kisspeptin-10 — PubChem molecular identity

  2. Activation of gonadotropin-releasing hormone neurons by kisspeptin as a neuroendocrine switch for the onset of puberty.

    Han SK, Gottsch ML, Lee KJ, Popa SM, Smith JT, Jakawich SK, Clifton DK, Steiner RA, Herbison AE · 2005 · The Journal of neuroscience : the official journal of the Society for Neuroscience

    DOI: 10.1523/jneurosci.3328-05.2005

Specifications and packaging

Nominal variant content; analytical results belong to the documented batch.

Material type
Peptide
Molecular formula (literature identity)
C63H83N17O14
Molecular weight (literature identity)
1302.4 g/mol

Quality and analyses

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Purity
>99%
Type
Declared specification

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