BLOPEPBOLANG BIOTECHNOLOGY

Lysine–proline–valine tripeptide

KPV

KPV is a tripeptide investigated in inflammatory models. The cited study uses a nanoparticle delivery system in colitis models; that formulation is not this catalog material.

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Mechanism and findings →

Mechanism and findings

Mixed · Study formulation · Cell assays and mouse colitis model

Formulation-dependent delivery

The tested intervention used hyaluronic-acid-functionalized nanoparticles in a hydrogel; results do not establish equivalence to unformulated KPV.

Xiao et al., 2017 →

Literature findings; refer to the model and formulation studied.

Mechanism of action

KPV — lysine–proline–valine tripeptide. The literature identity must be matched to the documented chemical form and composition of the supplied material.

The study used hyaluronic-acid-functionalized nanoparticles containing KPV within a hydrogel. Delivery to colonic epithelial cells and macrophages is part of the intervention; inflammation and mucosal-healing findings cannot be attributed solely to free KPV.

  • Inflammatory signaling

Xiao et al., 2017

Studied findings 1
Mixed · Study formulation

Formulation-dependent delivery

Cell assays and mouse colitis model

The tested intervention used hyaluronic-acid-functionalized nanoparticles in a hydrogel; results do not establish equivalence to unformulated KPV.

View context
Study design
Original-study abstract; experimental design described in linked source
Sample scope / arm
Not extracted; consult original study
Comparator
See original-study context
Experimental context (not instructions for use)
Abstract-level extraction; full methods and tables still require review.
Source section / table / abstract
Abstract

Evidence concerns the studied material and model, not the supplied BLOPEP batch.

Xiao et al., 2017

Sources and studies 1Peptide Monographs
  1. Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis.

    Xiao B, Xu Z, Viennois E, Zhang Y, Zhang Z, Zhang M, Han MK, Kang Y, Merlin D · 2017 · Molecular therapy : the journal of the American Society of Gene Therapy

    DOI: 10.1016/j.ymthe.2016.11.020

Specifications and packaging

Nominal variant content; analytical results belong to the documented batch.

Material type
Peptide

Quality and analyses

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Purity
>99%
Type
Declared specification

Published batches

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Storage

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