BLOPEPBOLANG BIOTECHNOLOGY

Modified growth hormone fragment

AOD-9604

AOD-9604 is a modified growth hormone fragment studied in lipid metabolism in obese and beta-3-adrenoceptor knockout mice.

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Mechanism and findings →

Mechanism and findings

Animal study · Study formulation · Obese and beta-3-adrenoceptor knockout mice

Lipid metabolism

Responses differed between chronic and acute experiments; the authors did not identify direct mediation through beta-3 receptors.

Heffernan et al., 2001 →

Literature findings; refer to the model and formulation studied.

Mechanism of action

AOD-9604 — modified growth hormone fragment. The literature identity must be matched to the documented chemical form and composition of the supplied material.

Experiments compared acute and chronic lipid responses in mice, including animals lacking the beta-3-adrenoceptor. Increased receptor expression may contribute to lipolytic sensitivity, but the authors did not conclude that AOD-9604 acted directly through that receptor.

  • Lipid metabolism

Heffernan et al., 2001

Studied findings 1
Animal study · Study formulation

Lipid metabolism

Obese and beta-3-adrenoceptor knockout mice

Responses differed between chronic and acute experiments; the authors did not identify direct mediation through beta-3 receptors.

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Study design
Original-study abstract; experimental design described in linked source
Sample scope / arm
Not extracted; consult original study
Comparator
See original-study context
Experimental context (not instructions for use)
Abstract-level extraction; full methods and tables still require review.
Source section / table / abstract
Abstract

Evidence concerns the studied material and model, not the supplied BLOPEP batch.

Heffernan et al., 2001

Sources and studies 1
  1. The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice.

    Heffernan M, Summers RJ, Thorburn A, Ogru E, Gianello R, Jiang WJ, Ng FM · 2001 · Endocrinology

    DOI: 10.1210/endo.142.12.8522

Specifications and packaging

Nominal variant content; analytical results belong to the documented batch.

Material type
Peptide

Quality and analyses

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Purity
>99%
Type
Declared specification

Published batches

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Storage

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